Ppt policitemia neonatal powerpoint presentation free. Two patients in the series of erf 1956 were brothers and 3 others had a definite family history. The key clinical consequence of polycythemia vera is the risk of blood clots or bleeding. New guidelines from the nccn for polycythemia vera. Polycythemia, defined as a venous hematocrit hct 65%, occurs in about 4% of. Policitemia vera caracterizacao clinica e molecular e novas.
Policitemia primaria policitemia vera pcv, policitemia rubra vera prv, eritremia por alison n. Municipal agreements for provision of police services by o. Polycythemia and hyperviscosity in the newborn saint lukes. Caso clinico poliglobulia hipertension globulo rojo. Carlos concha rend n neonat logo hospital antonio lorena policitemia neonatal definici n. They may also cause bleeding problems and make clots form in blood vessels. Relativas, absolutas, primarias, secundarias, adquiridas, congenitas. The number of white blood cells and platelets may also increase. A disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to thicken. Most of the health concerns associated with polycythemia vera are caused by the blood being thicker as a result of the increased red blood cells. Polycythemia or an increased hematocrit is associated with hyperviscosity of. The extra blood cells may collect in the spleen and cause it to become enlarged. To reassess the natural history of polycythemia vera and to obtain reliable estimates of both incidence of thrombosis and survival for use in defining the sample size for therapeutic clinical trials.
Polycythemia in the newborn is defined as either venous hematocrit or hemoglobin levels above 65% and 22 gdl, respectively 1234. Other significant diseaserelated symptoms include headaches, microvascular complications, and pruritus. Polycythemia vera pv is a chronic myeloproliferative neoplasm associated with jak2 mutations v617f or exon 12 in almost all cases. How i treat polycythemia vera blood american society. The average age of patients with polycythemia vera is 60 years. Per chi e affetto o conosce qualcuno affetto da questa patologia. Significance of jak2 burden in polycythemia vera treatment remains uncertain. Jun 20, 2016 policitemia primaria o policitemia vera 14. Polycythemia occurs when a babys blood has more red cells than normal. Pdf polycythemia is defined as a venous hematocrit of over 65%. Neonatal polycythemia is characterized by a venous hematocrit hct that greatly exceeds normal values for gestational and postnatal age. Lawrence and goetsch 1950 described 3 affected sibs. It may also result in the overproduction of white blood cells and platelets most of the health concerns associated with polycythemia vera are caused by the blood being thicker as a result of the increased red blood cells. Ppt policitemia neonatal powerpoint presentation free to.
Hipoxia cronica, como a causada pela vida em altitudes elevadas, por doenca cardiaca cianosante e por hipoxia cronica por doenca pulmonar. Download fulltext pdf spontaneous spinal epidural hematoma as the initial presentation of polycythemia vera article pdf available in acta haematologica 1231. It can be due to an increase in the number of red blood cells absolute polycythemia or to a decrease in the volume of plasma relative polycythemia. Eitrocitosis poliglobulia, policitemia y pseudoeritrocitosis falsa eritrocitosis. It may also result in the overproduction of white blood cells and platelets. The incidence of chronic myelogenous leukemia increases after age 50. Its the opposite of anemia, which is caused by too few red cells. Polycythemia and hyperviscosity in the newborn saint. Policitemia eritrocitosis by carolina arboleda on prezi. Eritrocitose idiopatica uma condicao nunca esclarecida policitemia vera. Per scambiarsi esperienze, opinioni e chissa magari. Download as ppt, pdf, txt or read online from scribd.
Policitemia vera university of california, san diego. Modan 1965 suggested that in only 2 reports of familial pv was the diagnosis completely documented lawrence and goetsch, 1950. The world health organization has defined the criteria for diagnosis, but it is still unclear which parameter hemoglobin or hematocrit is the most reliable for demonstrating increased red cell volume and for monitoring response to therapy. Patients with polycythemia vera have the potential to develop more advanced chronic blood diseases, such as myelofibrosis or even acute leukemia.
Owen 1924 emphasized the familial nature of polycythemia vera and presented a possible example. Any infant with symptoms that may be due to polycythemia. Policitemias y policitemia vera linkedin slideshare. Dec 02, 2016 polycythaemia vera pv is a clonal haematological malignancy characterised by pronounced symptoms, including fatigue, pruritus and symptomatic splenomegaly, along with an increased risk of thrombosis and the potential for evolution to myelofibrosis and secondary acute myeloid leukemia. Baixe no formato pdf, txt ou leia online no scribd. Policitemia neonatal researchgate, the professional network for scientists.
Polycythemia vera is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. Pdf spontaneous spinal epidural hematoma as the initial. A free powerpoint ppt presentation displayed as a flash slide show on id. Ademas refiere tos con sibilancias, niega dolor precordial, fiebre o escalofros. Polycythemia also known as polycythaemia or polyglobulia is a disease state in which the hematocrit the volume percentage of red blood cells in the blood is elevated.1178 1293 420 480 1412 760 375 1416 1455 1584 1309 871 1062 1534 940 1313 1605 765 1478 437 430 1564 1439 775 331 286 1123 1491 484 1386 1146 453 1076 438 1394